Evaluation of the Primus Ultra2 HPLC system for HbA2 measurement and ß-thalassemia screening
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چکیده
منابع مشابه
the evaluation and comparison of two esp textbooks available on the iranian market for teaching english to the students of medicine
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15 صفحه اولScreening cord blood for hemoglobinopathies and thalassemia by HPLC.
We evaluated the use of an HPLC method for screening hemoglobins in cord blood. We studied the genotype frequencies of the structural hemoglobin variants HbS and HbC and the synthesis variants alpha- and beta(+)-thalassemia in babies born on Curaçao. During three months, 67.2% of all (748) newborns were screened: 122 (24.3%) had an abnormal hemoglobin pattern, of which 53 (43.4%) had a hemoglob...
متن کاملLow HbA2 Level in β-Thalassemia Trait
Dr. Köseler and her colleagues reported the presence of δthalassemia in 3 out of 12 patients carrying the β-thalassemia trait with low HbA2 in the recent issue of this journal without giving any explanations for the remaining 9 cases (2012; 29: 289-290) [1]. I wish that they would also look for the presence of αthalassemia, at least in those 9 cases, because this seems to be the more prevalent ...
متن کاملEvaluation of an automatic HPLC analyser for thalassemia and haemoglobin variants screening
In this paper the authors report the evolution of a new automatic HPLC analyser for screening haemoglobinopathies. HbA(2) and F determinations are accurate and reproducible. The analysis time is short (6.5 min) and there is a good separation between the HbA(2) values of beta-thalassemia carriers from normals and alpha-thalassemia carriers, with no overlap between these groups. In addition, the ...
متن کاملPremarital genetic screening for beta thalassemia carrier status of indexed families using HbA2 electrophoresis.
OBJECTIVE To devise a strategy for prevention of beta thalassemia in newborns through reliable screening of indexed families. METHODS The cross-sectional study was conducted over six months in 2011 and comprised blood samples collected from subjects belonging to different ethnic groups from families of beta thalassemia major children registered with the Abbottonian Medical Association Blood C...
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ژورنال
عنوان ژورنال: Biochemia Medica
سال: 2008
ISSN: 1846-7482
DOI: 10.11613/bm.2008.031